Table 2 Sanger sequencing confirmed somatic mutations with increased frequencies in tumor samples

chr10:106124579

CCDC147

nonsynonymous SNV

0.31

0.45

0.52

c.G529T

p.A177S

0.29

0.40

0.71

0.76

chr17:38173081

CSF3

nonsynonymous SNV

0.26

0.49

0.66

c.C493T

p.P162S

0.61

0.23

0.43

0.58

chr15:64496758

CSNK1G1

nonsynonymous SNV

0.31

0.50

0.48

c.C881G

p.R294T

1.00

0.46

0.57

0.57

chr17:11696980

DNAH9

nonsynonymous SNV

0.24

0.42

0.62

c.A8222C

p.D2741A

0.12

0.21

0.36

0.56

chr4:88533803

DSPP

nonsynonymous SNV

0.27

0.61

0.52

c.T465A

p.N155K

0.96

0.20

0.51

0.45

chr20:33874597

FAM83C

nonsynonymous SNV

0.16

0.44

0.40

c.G1985A

p.T662M

0.00

0.17

0.30

0.38

chr6:5369392

FARS2

nonsynonymous SNV

0.2

0.36

0.35

c.G589A

p.V197M

1.00

0.16

0.35

0.36

chr14:25076412

GZMH

nonsynonymous SNV

0.17

0.40

0.37

c.G540T

p.Y180X

NA

0.15

0.28

0.33

chr10:126477647

METTL10

nonsynonymous SNV

0.14

0.57

0.60

c.T256C

p.I86V

0.06

0.19

0.58

0.40

chrX:153040228

PLXNB3

nonsynonymous SNV

0.17

0.21

0.19

c.G3898C

p.G1323R

0.06

0.29

0.33

0.37

chr12:3692299

PRMT8

nonsynonymous SNV

0.30

0.55

0.55

c.G904A

p.D302N

1.00

0.35

0.57

0.58

chr2:65316194

RAB1A

nonsynonymous SNV

0.18

0.37

0.39

c.T299C

p.N100S

0.00

0.23

0.62

0.54

chr7:122338859

RNF133

nonsynonymous SNV

0.17

0.36

0.34

c.C114T

p.W38X

NA

0.15

0.32

0.40

chrX:30870990

TAB3

nonsynonymous SNV

0.09

0.37

0.39

c.C1615T

p.E539K

0.07

0.15

0.33

0.36

chr1:234565362

TARBP1

nonsynonymous SNV

0.28

0.50

0.53

c.C2671T

p.D891N

1.00

0.34

0.45

0.57

chr17:7579358

TP53

nonsynonymous SNV

0.21

0.47

0.68

c.C329G

p.R110P

0.85

0.02

0.44

0.47

chr7:158824649

VIPR2

nonsynonymous SNV

0.13

0.63

0.59

c.G1081T

p.L361M

1.00

0.03

0.72

0.77

chr16:72828578

ZFHX3

nonsynonymous SNV

0.23

0.54

0.58

c.C8003T

p.R1754Q

0.45

0.17

0.56

0.53

chr19:58420819

ZNF417

nonsynonymous SNV

0.19

0.56

0.5

c.G827C

p.S276C

0.89

0.15

0.41

0.42

chr17:29554310

NF1

splice site SNV

0.16

0.56

0.48

c.G2325+1A

NA

NA

0.18

0.12

0.63

chr19:46192605

SNRPD2

splice site SNV

0.31

0.58

0.55

c.G3-781A

NA

NA

0.26

0.62

0.63

chr3:195022735-195022753

ACAP2

frameshift deletion

0. 15

0.41

0.55

c.1267_1285del

p.R423Wfs*26

NA

NA

NA

NA

chr1:201983017-201983030

ELF3

frameshift deletion

0.17

0.15

0.34

c.866_879del

p.N289Kfs*7

NA

NA

NA

NA

chr13:108922263-108922263

TNFSF13B

frameshift deletion

0.17

0.36

0.31

c.20delG

p.E8Sfs*15

NA

0.21

0.22

0.37