Figure 4
From: Exome profiling of primary, metastatic and recurrent ovarian carcinomas in a BRCA1-positive patient
Copy number variants in the ovarian tumors. Filtered CNVs in the OV, OMN, and REC tumors across the genome, with chromosomal labels at the top. Because we are only interested in large scale deletions and amplifications, smaller CNV calls were removed and adjacent segments were merged. In the heat map, red indicates amplifications and blue indicates deletions. The magnified CNV patterns from OV, to OMN, to REC are likely due to differences in tumor purity. Notable amplifications are seen in 8q and 11q. Deletions are seen in chr4, 6q, 7q, 12q, 16q, chr17, chr19, chr22.