Figure 5From: Alcohol dehydrogenase, iron containing, 1promoter hypermethylation associated with colorectal cancer differentiation Localization of ADHFE1 in normal colorectal mucosa (×200). (A) The ADHFE1 expression was detected predominantly in the apex of the crypts. It was noted to be decreased toward the bottom of the crypts. (B) A strong expression of ADHFE1 can be observed in the Paneth cells (arrow).Back to article page