Figure 4
From: Targeting Id1 reduces proliferation and invasion in aggressive human salivary gland cancer cells
Effects of Id2 knockdown on proliferation and invasiveness of ACCM cells. (A) Western blot shows the effects of Id2 knockdown (Id2AS) on the expression of the cell proliferation markers c-myc and p21. (B) Effect of Id2 knockdown on the proliferation of ACCM cells was determined in 10% serum or serum-free medium (0%) after 48 h. (C) Effect of Id2 knockdown on cell invasiveness was determined using Boyden chamber invasion assays. Data represent the average of 6 independent experiments and are presented as percentage of controls (ctl). * indicates significant differences between cell populations (p < 0.05, Student’s t test).