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Table 1 Cox regression analysis for factors possibly influencing disease-specific survival in patients with ESCC in our cohort

From: Wdr66 is a novel marker for risk stratification and involved in epithelial-mesenchymal transition of esophageal squamous cell carcinoma

Variables

Hazard ratio

95% CI

P

WDR66 (high vs low)

2.644

1.034-6.758

0.042

Gender (male vs female)

1.15

0.380-3.48

0.804

Age, y (<60 vs ≥60)

1.46

0.569-3.748

0.432

Tumor differentiation (high grade vs low or Intermediate grade)

2.763

1.093-6.983

0.032

pT factor ( pT3 or pT4 vs pT1 or pT2)

2.133

0.613-7.420

0.234

Lymph node metastasis (yes vs no)

1.575

0.362-6.852

0.545

Distant metastasis (yes vs no)

1.376

0.492-3.846

0.543

TNM stage (I or II vs III or IV)

7.711

2.181-27.259

0.002