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Table 1 Patient demographics and baseline clinical characteristics (safety population)

From: Results of a phase I dose escalation study of eltrombopag in patients with advanced soft tissue sarcoma receiving doxorubicin and ifosfamide

Demographics

No

Eltrombopag

Eltrombopag

Eltrombopag

Total

 

Eltrombopag

75 mg

100 mg

150 mg

(N = 15)

 

(n = 3)a

(n = 7)

(n = 4)

(n = 1)

 

Median age, y (range)

56.0 (20–65)

48.0 (38–62)

30.5 (23–44)

59.0

44.0 (20–65)

Gender, n (%)

     

 Female

1 (33)

4 (57)

2 (50)

1 (100)

8 (53)

 Male

2 (67)

3 (43)

2 (50)

0 (0)

7 (47)

Race, n (%)

     

 Hispanic or Latino

1 (33)

0 (0)

2 (50)

0 (0)

3 (20)

 Not Hispanic or Latino

2 (67)

7 (100)

2 (50)

1 (100)

12 (80)

Baseline clinical characteristics

   

Median baseline platelet count, 1000/μL (range)

256.0

300.0

264.0

388.0

281.0

(218–371)

(197–368)

(180–595)

 

(180–595)

ECOG PS

     

 ECOG 0, n (%)

0 (0)

6 (86)

0 (0)

1 (100)

7 (47)

 ECOG 1, n (%)

3 (100)

1 (14)

4 (100)

0 (0)

8 (53)

  1. aPatients were withdrawn prior to receiving eltrombopag during the second cycle.
  2. ECOG PS, Eastern Cooperative Oncology Group Performance Status.