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Table 1 The physiochemical characteristics of the liposomal formulated decitabine

From: Development of a novel cell-based assay system EPISSAY for screening epigenetic drugs and liposome formulated decitabine

Sample Mean diameter, nm (± SD) PDI Zeta potential, mV (± SD)
Decitabine-loaded liposomes 871 ± 69 0.358 -69.9 ± 2.8
Decitabine-loaded liposomes (E) 138 ± 5 0.296 -40.2 ± 4.3
Drug-free liposomes (MLVS) 1070 ± 77 0.744 -60.6 ± 2.7
Drug-free liposomes (E) 146 ± 1.6 0.137 -56.8 ± 0.9
  1. *E: unilamellar liposomes extruded using 200 and 400 nm polycarbonate membranes.
  2. PDI: polydispersity index.
  3. MLVs: multilamellar vesicles.