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Table 3 Quality of life scores at baseline and at completion of induction chemotherapy (scored by patients from 0 to 100 using the EORTC QLQ-C30 v.3)

From: Multicenter phase II study of weekly docetaxel, cisplatin, and S-1 (TPS) induction chemotherapy for locally advanced squamous cell cancer of the head and neck

Functional parameter

Scores at baseline

Scores after completion of 3 cycles of induction chemotherapy

pvalue

Global

   

 Global health status/QoL

56.1

53

NS

Functional scales

   

 Physical functioning

84.7

89.7

NS

 Role functioning

89

90.9

NS

 Emotional functioning

80.2

94.2

< 0.05

 Cognitive functioning

85.2

94.2

NS

 Social functioning

77.1

83.8

NS

Symptom scales/items

   

 Fatigue

19.5

24.5

NS

 Nausea and vomiting

3.4

9.7

< 0.05

 Pain

17.2

10.3

NS

 Dyspnea

11.4

11.4

NS

 Insomnia

16

16

NS

 Appetite loss

17.2

29.8

NS

 Constipation

6.8

11.4

NS

 Diarrhoea

3.4

10.3

NS

 Financial difficulties

26.4

36.7

NS