Skip to main content

Table 3 Course of Quality of Life as assessed in 21 ovarian cancer patients with the EORTC Quality of Life core questionnaire (QLQ-C30)

From: Monitoring physical and psychosocial symptom trajectories in ovarian cancer patients receiving chemotherapy

EORTC QLQ-C30c
  Baselinea CT3b CT6 AC1b AC2 constant term/
beta coefficient
Physical Functioning (PF) 53.7 (27.3) 62.0 65.9 78.5 93.9 (8.7) 50.1/5.9 t = 7.31; p < 0.001
Social Functioning (SF) 34.1 (26.6) 53.9 63.7 76.5 86.1 (15.6) 34.3/7.2 t = 7.29; p < 0.001
Role Functioning (RF) 40.5 (35.2) 36.3 47.1 62.0 77.8 (27.8) 32.0/5.0 t = 3.74; p < 0.001
Emotional Functioning (EF) 47.6 (24.6) 64.2 69.6 79.9 87.5 (15.7) 49.0/5.3 t = 5.93; p < 0.001
Cognitive Functioning (CF) 77.0 (25.5) 73.5 86.3 86.3 90.3 (16.6) 75.0/2.0 t = 2.22; p = 0.031
Global QOL (GQOL) 47.5 (14.3) 56.4 59.8 58.3 60.4 (29.3) 49.0/1.9 t = 2.405; p = 0.019
Fatigue (FA) 66.1 (28.2) 51.6 51.6 33.3 16.2 (16.8) 67.2/-6.3 t = -6.18; p < 0.001
Nausea/Vomiting (NV) 23.8 (30.1) 15.6 14.7 2.8 5.6 (13.0) 23.1/-3.0 t = -3.35; p = 0.002
Pain (PA) 46.0 (37.6) 35.3 33.3 25.9 10.6 (13.5) 47.9/-4.8 t = -4.18; p < 0.001
Dyspnoe (DY) 19.0 (34.3) 13.7 23.5 7.4 8.3 (20.7) 18.5/-1.5 t = -1.36; p = 0.178
Sleeping Disturbances (SD) 38.1 (38.4) 35.3 23.5 55.6 13.9 (33.2) 39.5/-3.1 t = -1.91; p = 0.062
Appetite Loss (AP) 57.1 (42.4) 5.9 21.6 7.4 0.0 (0.0) 31.0/-4.0 t = -3.04; p = 0.006
Constipation (CO) 25.0 (35.7) 15.7 27.5 14.8 6.1 (20.1) 23.9/-2.0 t = -1.60; p = 0.116
Diarrhea (DI) 16.7 (29.6) 11.8 8.3 9.3 0.0 (0.0) 12.2/-0.7 t = -1.43; p = 0.167
Financial Impact (FI) 19.0 (30.9) 25.5 13.7 5.9 2.8 (9.6) 23.8/-2.9 t = -3.12; p = 0.003
  1. a Baseline (CT1)
  2. b CT chemotherapy cycle, AC aftercare
  3. c Reference values (general German population, female) [53]: PF = 88.7 (17.5), SF = 90.3 (20.1), RF = 86.6 (23.7), EF = 76.3 (22.2), CF = 90.1 (18.4), GQOL = 69.2 (21.9); FA = 19.5 (23.1), NV = 3.6 (11.4), PA = 17.2 (25.3), DY = 9.1 (21.6), SD = 19.1 (29.0), AP = 6.3 (17.4), CO = 4.3 (14.9), DI = 3.1 (12.6), FI = 6.3 (18.6)