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Table 6 Correlation between estrogen and progesterone receptor status and MembErbB-2 expression

From: Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer

  MembErbB-2 (IF)a, n (%) Total N (%) P value MembErbB-2 (IHC)b, n (%) Total N (%) P value
  Negative Positive    Negative Positive   
ERc expression         
   Negative 54 (23.90)d 20 (8.8) 74 (32.7) 0.001e 54 (26.8) 16 (8.0) 70 (34.8) 0.002
   Positive 140 (61.9) 12 (5.3) 152 (67.3)   121 (60.2) 10 (5.0) 131 (65.2)  
PRf expression         
   Negative 90 (39.8) 24 (10.6) 114 (50.4) 0.003 88 (43.8) 20 (10.0) 108 (53.7) 0.011
   Positive 104 (46.0) 8 (3.5) 112 (49.6)   87 (43.2) 6 (3.0) 93 (46.2)  
  1. a IF: Immunofluorescence staining performed with C-18 antibody. b IHC: Immunohistochemistry staining performed with RBT-HER2 antibody. c ER: Estrogen receptor. d Percentage of the total cohort. e Correlation between variables was determined by χ2 analysis. f PR: Progesterone receptor