From: Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
MembErbB-2 (IF)a, n (%) | Total N (%) | P value | MembErbB-2 (IHC)b, n (%) | Total N (%) | P value | |||
---|---|---|---|---|---|---|---|---|
Negative | Positive | Negative | Positive | |||||
ERc expression | ||||||||
Negative | 54 (23.90)d | 20 (8.8) | 74 (32.7) | 0.001e | 54 (26.8) | 16 (8.0) | 70 (34.8) | 0.002 |
Positive | 140 (61.9) | 12 (5.3) | 152 (67.3) | 121 (60.2) | 10 (5.0) | 131 (65.2) | ||
PRf expression | ||||||||
Negative | 90 (39.8) | 24 (10.6) | 114 (50.4) | 0.003 | 88 (43.8) | 20 (10.0) | 108 (53.7) | 0.011 |
Positive | 104 (46.0) | 8 (3.5) | 112 (49.6) | 87 (43.2) | 6 (3.0) | 93 (46.2) |