Table 4 Correlation between NuclErbB-2 and MembErbB-2 expression studied by immunofluorescence with C-18 antibody
From: Clinical relevance of ErbB-2/HER2 nuclear expression in breast cancer
MembErbB-2, n (%) | Total N (%) | P value | ||
|---|---|---|---|---|
Negative | Positive | |||
NuclErbB-2 expression in the 226 patient cohort | ||||
Negative (0/1+) | 126 (55.7)a | 24 (10.6) | 150 (66.4) | 0.265b |
Positive (2+/3+) | 68 (30.0) | 8 (3.7) | 76 (33.6) | |
Total N (%) | 194 (85.8) | 32 (14.2) | 226 (100) | |
Negative (0) | 87 (38.5) | 19 (8.4) | 106 (46.9) | 0.127 |
Positive (1+/2+/3+) | 107 (47.4) | 13 (5.7) | 120 (53.1) | |
Total N (%) | 194 (85.8) | 32 (14.2) | 226 (100) | |
NuclErbB-2 expression in the 298 patient cohort c | ||||
Negative (0/1+) | 171 (57.5) | 30 (10.0) | 201 (67.4) | 0.176 |
Positive (2+/3+) | 88 (29.5) | 9 (3.0) | 97 (32.6) | |
Total N (%) | 259 (86.9) | 39 (13.1) | 298 (100) | |