Figure 3From: Regulation of p14ARF expression by miR-24: a potential mechanism compromising the p53 response during retinoblastoma development Role of the proteasome in ARF regulation. Western Blot analysis of ARF and p21 in retinoblastoma cell lines after MG132 treatment. Retinoblastoma cell lines were treated with the proteasome inhibitor MG132 for 10 hours. p21 was used as a positive control since its degradation is regulated by the ubiquitin-proteasome pathway.Back to article page