Predictive models for mutations in mismatch repair genes: implication for genetic counseling in developing countries

Table 1 Demographic, clinical and mutation characteristics of the sample

Characteristic	Category	N	(%)
Age at CRC diagnosis	Under 30 yrs old	13	14.8
	31-50 yrs old	54	61.4
	Over 50 yrs old	21	23.9
Sex	Female	58	65.9
	Male	30	34.1
Ethnicity (self-reported)	White	55	62.5
	"Pardo"*	31	35.2
	Non-available	2	2.3
Place of Birth	Southeast	67	76.1
	Northeast	12	13.6
	South	3	3.4
	North	2	2.3
	Midwest	2	2,3
Colorectal tumor	Separate	78	88.6
	Synchronous	9	10.2
	Metachronous	1	1.1
Extracolonic tumors in proband	Endometrial	6	6.8
	Breast	3	3.4
	Stomach	2	2.3
	Small intestine	2	2.3
	Hepatic	1	1.1
	Pelvis renal and ureter	1	1.1
	Ovary	1	1.1
Classification according to family history	Bethesda Criteria	50	56.8
	Amsterdam Criteria	38	43.2
Patogenic mutations	None	57	64.8
	MLH1	15	17.0
	MSH2	16	18.2

ISSN: 1471-2407