Table 2 CEC, V-CEC, CEP trends within and among the chemotherapy courses

CEC

start of CT

reference

1^st wk of CT

−2.924

(-4.93,−0.92)

< 0.01

after 1^st wk of CT

−0.909

(-2.80,0.98)

0.35

before 1^st CT

−5.848

(-9.83,−1.86)

< 0.01

V-CEC

start of CT

reference

1^st wk of CT

−2.289

(-3.86,−0.72)

< 0.01

after 1^st wk of CT

−0.996

(-2.56,0.57)

0.21

before 1^st CT

−4.014

(-7.29,−0.73)

0.02

CEP

start of CT

reference

1^st wk of CT

−0.366

(-0.58,−0.15)

< 0.01

after 1^st wk of CT

−0.295

(-0.47,−0.12)

< 0.01

Trends among courses of chemotherapy

Measurement

Terms

Coefficient (cells/μL)

95% CI

p value

CEC

Linear

−0.609

(-1.12,-0.10)

0.02

V-CEC

Linear

−0.288

(-0.72,0.15)

0.19

CEP

Linear

0.194

(0.03,0.36)

0.02

Quadratic

−0.03

(-0.06,0.01)

0.02