|
Patient characteristics
|
Placebo
|
Cocculine
|
All patients
|
p
|
|---|
|
Total
|
217
|
214
|
431
| |
|
Age, years
| | | |
0.56*
|
|
Median (min-max)
|
52.8 (20–74)
|
53.3 (30–74)
|
52.8 (20–74)
| |
|
Delay from surgery (days)
| | | | |
|
Median (min-max)
|
27.50 (4.00–70.0)
|
27.0 (1.0–72.0)
|
27.0 (1.0–72.0)
|
0.90*
|
|
ECOG Performance Status
|
n = 197
|
n = 198
|
n = 395
|
0.64†
|
|
0, n (%)
|
177 (89.8)
|
175 (88.4)
|
352 (89.1)
| |
|
1, n (%)
|
20 (10.2)
|
23 (11.6)
|
43 (10.9)
| |
|
Nausea and vomiting susceptibility
|
n = 188
|
n = 189
|
n = 377
|
0.47†
|
|
Yes n (%)
|
63 (33.5)
|
70 (37.0)
|
133 (35.3)
| |
|
pT grade
|
n = 215
|
n = 211
|
n = 426
|
1.00††
|
|
T1 a-b-c, n(%)
|
119 (55.3)
|
118 (55.9)
|
237 (55.6)
| |
|
T2, n(%)
|
87 (40.5)
|
85 (40.3)
|
172 (40.4)
| |
|
T3, n(%)
|
7 (3.3)
|
7 (3.3)
|
14 (3.3)
| |
|
T4, n(%)
|
2 (0.9)
|
1 (0.5)
|
3 (0.7)
| |
|
pN grade
|
n = 213
|
n = 213
|
n = 426
|
0.84†
|
|
N-, n(%)
|
85 (39.9)
|
83 (39.0)
|
168 (39.4)
| |
|
N+, n(%)
|
128 (60.1)
|
130 (61.0)
|
258 (60.6)
| |
- *: Mann–Whitney U test; † : Person’s chi-square test; †† : Fischer test.
