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Table 3 Odds ratios of AR expression by testosterone tertiles in natural postmenopausal women with ER-positive breast cancer

From: Androgen receptors and serum testosterone levels identify different subsets of postmenopausal breast cancers

 

Testosterone tertiles, ng/ml

 
 

≤0.328

0.328-0.474

> 0.474

P trend

All ages

    

 AR expression

    

  Absent / poor-moderate

8/70

11/73

12/55

 

  age-adjusted OR (95% CI)

1

1.31 (0.50-3.46)

1.92 (0.73-5.02)

0.189

  High / poor-moderate

42/70

45/73

62/55

 

  age-adjusted OR (95% CI)

1

1.04 (0.61-1.77)

1.86 (1.10-3.16)

0.020

<65 years

    

 AR expression

    

  Absent / poor-moderate

3/27

6/39

5/25

 

  age-adjusted OR (95% CI)

1

1.38 (0.32-6.05)

2.03 (0.43-9.63)

0.374

  High / poor-moderate

18/27

23/39

21/25

 

  age-adjusted OR (95% CI)

1

0.88 (0.40-1.95)

1.26 (0.55-2.91)

0.582

≥65 years

    

 AR expression

    

  Absent / poor-moderate

5/43

5/34

7/30

 

  age-adjusted OR (95% CI)

1

1.25 (0.33-4.70)

2.00 (0.58-6.90)

0.282

  High / poor-moderate

24/43

22/34

41/30

 

  age-adjusted OR (95% CI)

1

1.13 (0.54-2.37)

2.42 (1.22-4.82)

0.011

  1. NOTES. Androgen receptor (AR) expression: absent, 0%; poor, ≥1 to 30%; moderate, >30 to 60%, high: >60%. Estrogen receptor (ER) -positive: ER expression ≥10%.
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BMC Cancer

ISSN: 1471-2407

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