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Table 3 Odds ratios of AR expression by testosterone tertiles in natural postmenopausal women with ER-positive breast cancer

From: Androgen receptors and serum testosterone levels identify different subsets of postmenopausal breast cancers

  Testosterone tertiles, ng/ml  
  ≤0.328 0.328-0.474 > 0.474 P trend
All ages     
 AR expression     
  Absent / poor-moderate 8/70 11/73 12/55  
  age-adjusted OR (95% CI) 1 1.31 (0.50-3.46) 1.92 (0.73-5.02) 0.189
  High / poor-moderate 42/70 45/73 62/55  
  age-adjusted OR (95% CI) 1 1.04 (0.61-1.77) 1.86 (1.10-3.16) 0.020
<65 years     
 AR expression     
  Absent / poor-moderate 3/27 6/39 5/25  
  age-adjusted OR (95% CI) 1 1.38 (0.32-6.05) 2.03 (0.43-9.63) 0.374
  High / poor-moderate 18/27 23/39 21/25  
  age-adjusted OR (95% CI) 1 0.88 (0.40-1.95) 1.26 (0.55-2.91) 0.582
≥65 years     
 AR expression     
  Absent / poor-moderate 5/43 5/34 7/30  
  age-adjusted OR (95% CI) 1 1.25 (0.33-4.70) 2.00 (0.58-6.90) 0.282
  High / poor-moderate 24/43 22/34 41/30  
  age-adjusted OR (95% CI) 1 1.13 (0.54-2.37) 2.42 (1.22-4.82) 0.011
  1. NOTES. Androgen receptor (AR) expression: absent, 0%; poor, ≥1 to 30%; moderate, >30 to 60%, high: >60%. Estrogen receptor (ER) -positive: ER expression ≥10%.