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Table 1 Comparison of clinical and pathologic characteristics of breast cancer patients according to the phospho-p90RSK expression

From: Phosphorylation of p90RSK is associated with increased response to neoadjuvant chemotherapy in ER-positive breast cancer

  

Low P90RSK

High P90RSK

 

Mean age

 

55.3 (±10.4)

48.3 (±11.9)

0.004

Initial tumor size (cm)

 

5.1 (±2.3)

5.2 (2.4)

0.734

cT stage

cT1-2

18 (55%)

38 (48%)

0.339

 

cT3-4

15 (45%)

41 (52%)

 

cN stage

cN0-1

21 (64%)

40 (51%)

0.149

 

cN2-3

12 (36%)

39 (49%)

 

pCR

pCR no

29 (88%)

72 (91%)

0.414

 

pCR yes

4 (12%)

7 (9%)

 

Estrogen receptor

ER negative

18 (55%)

42 (53%)

0.530

 

ER positive

15 (45%)

37 (47%)

 

Progesterone receptor

PR negative

10 (67%)

36 (64%)

0.560

 

PR positive

5 (33%)

20 (36%)

 

HER2 overexpression

HER2 negative

10 (67%)

39 (70%)

0.527

 

HER2 positive

5 (33%)

17 (30%)

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