Figure 1

Study design and patient recruitment (N = projected numbers). Notes: a) Questionnaires filled out by the patients; b) Structured Clinical Interview for DSM-IV applied by trained interviewers; c) HADS score for depression ≥ 8 & SCID-I diagnosis estimated in 20% of the cases (N = 240 eligible patients) of whom 75% are expected to be consent with randomization; d) Expected completer 80%, e) Expected completer 70%.