Figure 2
Cooperation between GNF-2 and AKIs in clonigenicity inhibition of Ba/F3 p185 Bcr-Abl T315I cells. Clonigenicity assay was performed as described in Materials and Methods. Ba/F3 transfected cells were treated with GNF-2 at 5, 25 and 100 μM, in the presence of 0.1 μM and 1 μM of Imatinib (A), Nilotinib (B) and Dasatinib (C). IC50 values +/− SD were calculated and listed (D).