Table 1 Correlations between FGF19 expression and clinicopathological parameters in 40 patients with HCC

Age

   < 65 years

23

0.007 ± 0.006

0.505

   ≥65 years

17

0.016 ± 0.014

Gender

   Male

31

0.014 ± 0.009

0.319

   Female

9

0.003 ± 0.002

Virus

   HBV

4

0.058 ± 0.058

0.808

   HCV

27

0.002 ± 0.001

   None

9

0.017 ± 0.016

Miran Criteria

   In

17

0.001 ± 0.000

0.194

   Out

23

0.0019 ± 0.011

AFP

   < 10 ng/mL

20

0.013 ± 0.012

0.194

   ≥ 10 ng/mL

20

0.009 ± 0.007

Tumor size

   < 5 cm

20

0.001 ± 0.000

0.137

   ≥5 cm

20

0.021 ± 0.013

Histologic type of tumor

   Well differentiated

6

0.001 ± 0.001

0.808

   Moderately differentiated

31

0.014 ± 0.009

   Poorly differentiated

3

0.002 ± 0.001

Formation of fibrous capsule

   Present

39

0.011 ± 0.007

-------

   Absent

1

0.0002

Capsular infiltration

   Present

38

0.012 ± 0.007

0.718

   Absent

2

0.0003 ± 0.0003

Septal formation

   Present

30

0.014 ± 0.009

0.445

   Absent

10

0.002 ± 0.002

Serosal invasion

   Present

1

0.016

-------

   Absent

39

0.011 ± 0.007

Portal invasion

   Present

30

0.014 ± 0.009

0.449

   Absent

10

0.002 ± 0.002

Hepatic vein invasion

   Present

10

0.024 ± 0.023

0.269

   Absent

30

0.007 ± 0.005

Intrahepatic metastasis

0.580

   Present

22

0.008 ± 0.006

   Absent

18

0.015 ± 0.013

Bile duct invasion

   Present

1

0.232

-------

   Absent

39

0.005 ± 0.004

Lymph node metastasis

   Present

1

0.001

-------

   Absent

39

0.011 ± 0.007

Pathological stage

   II

7

0.0004 ± 0.0002

0.049

   III

14

0.020 ± 0.016

   IV

19

0.009 ± 0.007