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Figure 2 | BMC Cancer

Figure 2

From: Somatic mitochondrial DNA mutations in cancer escape purifying selection and high pathogenicity mutations lead to the oncocytic phenotype: pathogenicity analysis of reported somatic mtDNA mutations in tumors

Figure 2

Comparison to pathogenic mtDNA variants, all possible variants and population level variants. The distribution of pathogenicity scores of mtDNA variations in oncocytic tumors (red) and non-oncytic and general cancer (both blue) are compared to reported mtDNA pathogenic variations, all possible variations, and normal population variations (all gray). For details on the final three categories, see the text and [16]. With five tests, the corrected significance threshold is 0.01

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BMC Cancer

ISSN: 1471-2407

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