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Figure 4 | BMC Cancer

Figure 4

From: Spatial morphological and molecular differences within solid tumors may contribute to the failure of vascular disruptive agent treatments

Figure 4

Tumor cells in the periphery express mesenchymal markers. Formalin fixed liver sections with CRC liver metastases were stained with antibodies for EMT markers; E-cadherin (A), β-catenin (B), vimentin (C) and ZEB1 (D). Magnification scale bar=200μm. Arrows in A magnified inset indicates detached tumor cells not expressing E-cadherin. Arrows in B magnified inset indicates tumor cells displaying nuclear localization of β-catenin. Magnified inset in C indicates increased vimentin staining in the periphery. Magnified inset and arrows in D indicate tumor cells displaying nuclear localization of ZEB1.

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BMC Cancer

ISSN: 1471-2407

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