Skip to main content

Table 5 Breast cancer specific survival by Kaplan Meier analysis according to histopathological and molecular parameters

From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer

Variable

n

Means of survival time (years) / n

p-value, Log Rank

  

GASC1 negative

GASC1 positive

 

Overall

355

14.6/198

16.6/157

0.017 (0.012B, 0.013T-W)

Histological type

    

 Ductal

231

14.5/143

17.3/88

0.006

 Others

124

14.8/ 55

15.4/69

0.608

Tumor grade

    

 I

84

16.5/ 31

17.0/ 53

0.415

 II+III

269

14.3/165

16.0/104

0.087

 unknown

2

   

ER status

    

 negative

77

13.4/ 51

15.2/ 26

0.322

 positive

272

15.0/143

16.7/129

0.043 (0.027 B)

 unknown

6

   

PR status

    

 negative

137

13.6/ 91

16.5/ 46

0.061 (0.042 B)

 positive

212

15.4/103

16.5/109

0.251

 unknown

6

   

HER2 status

    

 negative

290

15.3/156

17.4/134

0.018 (0.003 B)

 positive

45

12.1/ 32

13.0/ 13

0.704

 unknown

20

   

HER2-/ductal/grade II

90

14.4/49

18.1/41

0.015

Triple negative

39

14.6/29

18.0/10

0.196

  1. p- value for test of equality of survival distributions for the different levels of GASC1, B: Breslow (Generalized Wilcoxon),T-W: Tarone –Ware, n – number of cases.