Skip to main content

Table 5 Breast cancer specific survival by Kaplan Meier analysis according to histopathological and molecular parameters

From: Histone demethylase GASC1 - a potential prognostic and predictive marker in invasive breast cancer

Variable n Means of survival time (years) / n p-value, Log Rank
   GASC1 negative GASC1 positive  
Overall 355 14.6/198 16.6/157 0.017 (0.012B, 0.013T-W)
Histological type     
 Ductal 231 14.5/143 17.3/88 0.006
 Others 124 14.8/ 55 15.4/69 0.608
Tumor grade     
 I 84 16.5/ 31 17.0/ 53 0.415
 II+III 269 14.3/165 16.0/104 0.087
 unknown 2    
ER status     
 negative 77 13.4/ 51 15.2/ 26 0.322
 positive 272 15.0/143 16.7/129 0.043 (0.027 B)
 unknown 6    
PR status     
 negative 137 13.6/ 91 16.5/ 46 0.061 (0.042 B)
 positive 212 15.4/103 16.5/109 0.251
 unknown 6    
HER2 status     
 negative 290 15.3/156 17.4/134 0.018 (0.003 B)
 positive 45 12.1/ 32 13.0/ 13 0.704
 unknown 20    
HER2-/ductal/grade II 90 14.4/49 18.1/41 0.015
Triple negative 39 14.6/29 18.0/10 0.196
  1. p- value for test of equality of survival distributions for the different levels of GASC1, B: Breslow (Generalized Wilcoxon),T-W: Tarone –Ware, n – number of cases.