Variable | Patients with herpes zoster | Matched- control subjects | Odds ratio | 95% CI | P value |
---|---|---|---|---|---|
Total | 42,498 | 169,983 | Â | Â | Â |
Follow-up | Â | Â | - | - | - |
Total person-years | 168,992 | 684,001 | Â | Â | Â |
Average person-years | 3.976 | 4.024 | Â | Â | Â |
Sex | Â | Â | - | - | 0.9874 |
Female | 52.4 | 52.4 | Â | Â | Â |
Male | 47.6 | 47.6 | Â | Â | Â |
Age, years-old | Â | Â | - | - | 1.0000 |
>= 60 | 40.0 | 40.0 | Â | Â | Â |
50-59 | 19.6 | 19.6 | Â | Â | Â |
40-49 | 12.9 | 12.9 | Â | Â | Â |
30-39 | 10.7 | 10.7 | Â | Â | Â |
< 30 | 16.6 | 16.6 | Â | Â | Â |
Comorbidities (%) | Â | Â | Â | Â | Â |
Myocardial infarct | 1.4 | 1.2 | 1.12 | 0.95-1.33 | 0.1846 |
Congestive heart failure | 4.6 | 3.7 | 1.28 | 1.18-1.39 | <0.0001 |
Peripheral vascular disease | 2.0 | 1.6 | 1.32 | 1.15-1.51 | <0.0001 |
Cerebrovascular disease | 10.5 | 9.5 | 1.19 | 1.13-1.25 | <0.0001 |
Dementia | 1.3 | 1.4 | 1.12 | 0.99-1.27 | 0.0667 |
Chronic pulmonary disease | 29.6 | 24.6 | 1.38 | 1.33-1.43 | <0.0001 |
Rheumatologic disease | 4.2 | 2.9 | 1.92 | 1.74-2.10 | <0.0001 |
Peptic ulcer disease | 25.7 | 21.2 | 1.40 | 1.35-1.45 | <0.0001 |
Mild liver disease | 18.0 | 15.0 | 1.33 | 1.27-1.39 | <0.0001 |
Diabetes (mild to moderate) | 13.3 | 11.1 | 1.33 | 1.28-1.39 | <0.0001 |
Diabetes (with chronic complications) | 4.0 | 3.2 | 1.36 | 1.26-1.47 | <0.0001 |
Hemiplegia or paraplegia | 1.0 | 1.1 | 1.13 | 0.94-1.36 | 0.1897 |
Renal disease | 6.0 | 4.8 | 1.43 | 1.33-1.54 | <0.0001 |
Moderate or severe liver disease | 0.4 | 0.4 | 1.09 | 0.82-1.45 | 0.9568 |