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Table 3 Multivariate Cox regression analysis of clinical variables on overall survival

From: Highly frequent PIK3CA amplification is associated with poor prognosis in gastric cancer

Variable

HR†

95% CI

P

PIK3CA amplification

2.59

1.39-4.82

0.003

Age1

1.28

0.98-1.67

0.07

Differentiation2

1.16

0.66-2.05

0.61

Lymph node metastasis3

2.70

1.01-7.21

0.047

TNM stage4

2.07

1.17-3.65

0.01

  1. † HR: Hazard Ratio
  2. 1 Age (per 10 years)
  3. 2 Differentiation (well or moderate; poor or no differentiation)
  4. 3 Lymph node metastasis (Yes vs. No)
  5. 4 Tumor stage (I; II; III; IV)