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Table 4 EORTC QLQ-C30 mean scores (SE) at each time point
| CR &TT at T0 | CR at T1 | TT at T1 | CR at T2 | TT at T2 | CR at T3 | TT at T3 | CR at T4 | TT at T4 | CR at T5 | TT at T5 | |
|---|---|---|---|---|---|---|---|---|---|---|---|
| n=121 | n=62 | n=59 | n=62 | n=59 | n=50 | n=51 | n=30 | n=36 | n=16 | n=18 | |
| physical functioning | 83,64 | 80,08 (1,64) | 79,39 (2,03) | 80,69 (1,70) | 82,03 (2,18) | 85,44 (1,96) | 83,64 (1,97) | 84,08 (3,50) | 88,69 (1,88) | 84,89 (3,29) | 89,89 (3,19) |
| role functioning | 68,32 | 66,93 (3,51) | 64,99 (4,22) | 75,70 (3,45) | 75,79 a (4,26) | 81,86 (4,62) | 84,65 (4,45) | 85,54 (5,73) | 94,08 (5,38) | 88,11 (9,41) | 97,49 (8,67) |
| cognitive functioning | 84,44 | 76,10 (2,82) | 77,77 (3,02) | 80,88 (2,50) | 81,27 (2,94) | 79,92 (3,60) | 83,77 (3,40) | 81,10 (4,26) | 85,95 (3,51) | 80,27 (3,23) | 86,52 (5,67) |
| emotional functioning | 76,65 | 75,96 (2,50) | 75,44 (2,60) | 75,56 (2,60) | 78,52 (2,74) | 76,65 (3,46) | 77,32 (2,80) | 76,65 (4,36) | 80,69 (4,14) | 77,69 (6,17) | 81,34 (4,50) |
| social functioning | 81,40 | 78,63 (2,10) | 71,71 (3,08) | 83,86 (2,64) | 82,55 a (2,89) | 89,39 (3,25) | 84,74 (3,69) | 92,52 (6,16) | 90,50 (4,48) | 92,86 (7,41) | 89,74 (6,97) |
| global health status | 68,11 | 67,00 (2,22) | 59,02 (2,90) | 68,52 (2,24) | 65,81 (3,09) | 72,28 (2,48) | 72,61 (3,14) | 72,28 (3,22) | 76,19 (3,78) | 74,36 (4,06) | 78,53 (5,30) |
| fatigue | 32,32 | 42,88 a (3,11) | 45,45 a (3,83) | 36,51 (2,45) | 33,28 a (3,93) | 30,93 (3,15) | 27,21 (3,58) | 24,55 (4,86) | 18,86 (3,71) | 21,91 (6,53) | 14,96 (5,55) |
| nausea & vomiting | 6,34 | 8,84 (3,16) | 13,31 (3,20) | 4,70 (2,77) | 7,20 (2,88) | 1,47 (3,29) | 4,67 (2,62) | 3,56 (3,30) | −0,23 (3,55) | 2,17 (5,99) | −2,00 (6,63) |
| pain | 24,52 | 21,74 (3,68) | 24,21 (3,45) | 20,42 (3,39) | 21,93 (3,93) | 16,53 (4,35) | 19,18 (3,55) | 17,85 (5,34) | 15,43 (4,11) | 15,14 (7,29) | 12,02 (7,38) |
| dyspnea | 13,22 | 17,11 (3,28) | 17,47 (2,45) | 24,15 (2,89) | 22,42 (4,08) | 18,08 (3,71) | 15,22 (3,62) | 14,33 (4,65) | 14,23 (3,97) | 19,47 (4,53) | 15,31 (5,67) |
| insomnia | 30,85 | 29,74 (3,96) | 30,25 (4,10) | 33,59 (4,43) | 31,43 (4,67) | 28,77 (4,59) | 26,19 (4,26) | 29,74 (6,08) | 19,74 (4,74) | 32,94 (6,43) | 26,69 (9,56) |
| loss of appetite | 11,57 | 11,01 (4,00) | 20,66 (4,36) | 8,84 (3,84) | 11,57 (3,18) | 0,46 (4,48) | 6,90 (2,86) | 11,57 a (6,19) | 1,47 (4,23) | 11,57 (8,05) | −5,10 (5,27) |
| obstipation | 11,85 | 14,07 (3,44) | 19,12 (4,03) | 12,94 (3,89) | 18,74 (3,55) | 14,62 (4,95) | 9,85 (3,86) | 5,18 (3,71) | 9,83 (4,34) | 7,68 (7,98) | −2,74 a (5,24) |
| diarrhea | 5,23 | 8,01 (2,89) | 8,26 (1,99) | 9,06 (3,41) | 9,83 (2,52) | 6,62 (2,97) | 5,90 (1,78) | 9,68 (3,48) | 1,19 (1,92) | 5,23 (0,00) | 7,32 (4,78) |
| financial difficulty | 11,29 | 15,18 (2,25) | 12,51 (2,59) | 14,57 (2,88) | 11,87 (2,24) | 15,46 (2,74) | 8,63 (2,99) | 14,63 (6,26) | 5,23 (4,22) | 15,46 (4,17) | 17,54 a (7,59) |
