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Table 2 Distribution of ApoE polymorphism among gastric cancer cases and controls

From: A case–control study on the effect of Apolipoprotein E genotypes on gastric cancer risk and progression

 

Cases ‡

Controls^

All cases

Intestinal (n=79)

Diffuse (n=57)

n (%)

n (%)

OR (95% CI)

OR (95% CI)

OR (95% CI)

ε3/ε3

109 (71.71)

253 (62.94)

1*

1*

1*

ε3/ε2

15 (9.87)

63 (15.67)

0.43 (0.21 -0.91)

0.34 (0.13 – 0.92)

0.57 (0.23 – 1.40)

ε3/ε4

27 (17.76)

75 (18.66)

0.70 (0.37 - 1.30)

0.75 (0.35 – 1.60)

0.64 (0.27 – 1.47)

ε2/ε2

0 (0.00)

5 (1.24)

NC

NC

NC

ε2/ε4

1 (0.66)

5 (1.24)

1.25 (0.10 - 15.10)

2.54 (0.21 – 31.17)

NC

ε4/ε4

0 (0.00)

1 (0.25)

NC

NC

NC

ε3/ε2 or ε2/ε2

15 (12.10)

68 (21.18)

0.40 (0.19 - 0.84)

0.31 (0.11 – 0.83)

0.53 (0.21 – 1.30)

ε3/ε4 or ε4/ε4

27 (19.85)

76 (23.10)

0.68 (0.36 - 1.26)

0.71 (0.34 – 1.53)

0.62 (0.27 – 1.43)

  1. ‡ Apolipoprotein genotype was measured in 152 cases.
  2. ^ Apolipoprotein genotype was measured in 402 controls.
  3. † OR adjusted by age, gender, alcohol consumption (as continuous variable), packyears of smoking, grilled meat consumption and family history of gastric cancer.
  4. * Reference category.
  5. NC: not calculable due to few many values.