Table 1 Odds ratio estimation to assess the association between breast cancer (BC) and DNA repair capacity (DRC) and other selected variables in women with BC (n=285) and women without BC (n=539)
From: The association of DNA Repair with breast cancer risk in women. A comparative observational study
Variable | Women with BC n (mean) | Women without BC n (mean) | Crude OR1 | Adjusted OR2 | P value |
|---|---|---|---|---|---|
(95% CI) | (95% CI) | ||||
Age (continuous)* | 285 (56.7) | 539 (52.4) | 1.02 (1.02,1.04) | 1.02 (1.01, 1.05) | 0.001 |
Number of children | 273(2.4) | 517 (2.1) | 1.2 (1.1, 1.3) | 1.1 (1.0, 1.3) | 0.055 |
# Missing (34) | |||||
Increasing BMI (continuous)* | 284 (27.8) | 534 (27.2) | 1.02 (0.9, 1.1) | 1.03 (1.0, 1.1) | 0.118 |
# Missing (6) | |||||
Family history of BC | |||||
Yes | 64 | 78 | 1.7 (1.2, 2.5) | 1.7 (1.0, 2.8) | 0.054 |
No | 221 | 461 | |||
Marital status | |||||
Married | 154 | 362 | Referent | Referent | |
Single | 61 | 92 | 4.2 (2.2, 7.8) | 5.9 (2.3, 15.6) | <0.001 |
Divorced | 40 | 66 | 2.7 (1.4, 5.3) | 3.6 (1.2, 10.5) | 0.025 |
Widow | 30 | 17 | 2.9 (1.4, 5.9) | 4.6 (1.6, 13.7) | 0.006 |
# Missing (2) | |||||
Irregular menstrual cycles | |||||
Yes | 183 | 320 | 1.2 (0.9,1.6) | 1.4 (0.8, 2.2) | 0.207 |
No | 102 | 213 | |||
# Missing (6) | |||||
History of pregnancy | |||||
Yes | 220 | 401 | 1.2 (0.8,1.6) | 1.4 (0.8,2.2) | 0.382 |
No | 65 | 138 | |||
History of breastfeeding | |||||
Yes | 122 | 246 | 0.8 (0.6, 1.1) | 0.8 (0.5, 1.2) | 0.256 |
No | 118 | 194 | |||
# Missing (144) | |||||
Alcohol intake | |||||
Yes | 42 | 98 | 0.8 (0.6, 1.2) | 0.8 (0.5, 1.7) | 0.526 |
No | 243 | 441 | |||
Smoking | |||||
Yes | 37 | 48 | 1.6 (0.9, 2.4) | 1.1 (0.6, 2.1) | 0.707 |
No | 248 | 491 | |||