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Table 1 Characteristics of 35 HER2 negative mBC patients treated with Bevacizumab plus Paclitaxel followed by maintenance Bevacizumab

From: Maintenance bevacizumab beyond first-line paclitaxel plus bevacizumab in patients with Her2-negative hormone receptor-positive metastatic breast cancer: efficacy in combination with hormonal therapy

Total number of patients (n = 35)

Frequency (%)

Median age (range)

50 (32–72)

Menopausal Status

 

 Pre

6 (17.1)

 Post

29 (82.9)

Hormonal Receptor Status

 

 Negative

5 (14.3)

  Positive

30 (85.7)

Triple negative

5 (14.3)

Adjuvant chemotherapy

 

- None

13 (37.1)

- including anthracyclines

9 (25.7)

- including antracyclines + taxanes

9 (25.7)

- Other regimens

4 (11.4)

Adjuvant hormonal therapy

22 (62.8)

Visceral metastatic sites

23 (65.7)

Median Disease Free Survival, months (range)

30 (0–362)

Median Cycles of Bevacizumab + Paclitaxel (range)

8 (6–12)

Median cycles of three-weekly mBev (range)

7 (1 – 28)

Median PS at the start of mBev (range)

0 (0–1)

  1. PS, Performance Status (ECOG); Triple negative, estrogen receptor, progesteron receptor, HER2 negative; mBev, mainteinance Bevacizumab.