Adherence evaluation of endocrine treatment in breast cancer: methodological aspects

BMC Cancer

Table 4 Overall adherence rates across methods

Assessment Method	Number of patients (%)
	Adherent	CL 95%
Plasma concentration ^a	98.2%	95-99%
Physician rating	92.1%*	88-95%
Prescription refill (6months)^b	85.3%*	78-90%
Self-rating	82.6%*⁺	77-87%
Overall prescription refill ^b	77.8%*⁺	70-83%

^a plasma concentrations below the quantification limit indicate non-adherence (see Methods section).
^b an MPR of >90% was classified as adherent.
* significant lower adherence rate than adherence rate indicated by plasma concentration.
⁺ significant lower adherence rate than adherence rate indicated by physician-rating.

ISSN: 1471-2407