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Table 7 Correlations between VEGF-C expression and clinicopathological characteristics

From: Expression and clinical significance of extracellular matrix protein 1 and vascular endothelial growth factor-C in lymphatic metastasis of human breast cancer

Clinicopathological characteristics N VEGF-C positive P VEGF-C mRNA expression level P
   N rate (%)    
Age (years)       
<60 30 23 76.7   2.41 ± 0.33  
≥ 60 11 10 90.9 0.412 3.20 ± 0.76 0.505
Histological grade
(invasive ductal)
      
I+II 16 14 87.5   2.72 ± 0.58  
III+IV 20 14 70.0 0.257 2.65 ± 0.45 0.908
Tumor size       
T1 15 12 80.0   3.00 ± 0.63  
T2 23 18 78.3   2.14 ± 0.31  
T3 3 3 100 0.670 4.58 ± 1.68 0.237
Lymph nodal status       
N0 22 20 90.9   2.92 ± 0.48  
N1 12 8 66.7   2.10 ± 0.53  
N2 5 3 60.0   2.51 ± 0.86  
N3 2 2 100 0.606 2.65 ± 0.07 0.710
Estrogen receptor status       
- 10 9 90.0   2.42 ± 0.63  
+~+++ 31 24 77.4 0.653 2.69 ± 0.38 0.606
Progesterone receptor status       
- 8 6 75.0   2.14 ± 0.75  
+~+++ 33 27 81.8 0.642 2.75 ± 0.35 0.217
HER2/neu score       
- (0-1) 13 10 76.9   2.70 ± 0.66  
+ (2-3) 28 23 82.1 0.693 2.60 ± 0.36 0.918
  1. "+", "++" and "+++" for VEGF-C immunochemistry staining was all grouped together as "+"