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Table 6 Correlations between ECM1 expression and clinicopathological characteristics

From: Expression and clinical significance of extracellular matrix protein 1 and vascular endothelial growth factor-C in lymphatic metastasis of human breast cancer

Clinicopathological characteristics N ECM1 positive P ECM1 mRNA expression P
   N rate (%)    
Age (years)       
< 60 30 22 73.3   1.54 ± 0.43  
≥ 60 11 9 81.8 0.700 0.68 ± 0.46 0.183
Histological grade
(invasive ductal)
      
I+II 16 12 75.0   1.76 ± 0.71  
III+IV 20 16 80.0 0.720 1.18 ± 0.39 0.483
Tumor size       
T1 15 10 66.7   1.49 ± 0.60  
T2 23 19 82.6   1.34 ± 0.46  
T3 3 2 66.7 0.512 0.11 ± 0.08 0.275
Lymph nodal status       
N0 22 16 72.7   1.48 ± 0.54  
N1 12 10 83.3   1.32 ± 0.58  
N2 5 3 60.0   0.81 ± 0.60  
N3 2 2 100 0.121 0.54 ± 0.50 0.424
Estrogen receptor status       
- 10 5 50.0   1.02 ± 0.62  
+~+++ 31 26 83.9 0.045* 1.40 ± 0.41 0.611
Progesterone receptor status       
- 8 4 50.0   1.32 ± 0.90  
+~+++ 33 27 81.8 0.082 1.30 ± 0.37 0.987
HER2/neu score       
- (0-1) 13 11 84.6   1.48 ± 0.69  
+ (2-3) 28 20 71.4 0.458 1.23 ± 0.39 0.757
  1. "+", "++" and "+++" for ECM1 immunochemistry staining was all grouped together as "+"
  2. * P < 0.05 is considered statistically significant