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Table 5 Comparison of VEGF-C expression levels between the metastasis- and non-metastasis groups

From: Expression and clinical significance of extracellular matrix protein 1 and vascular endothelial growth factor-C in lymphatic metastasis of human breast cancer

 

VEGF-C mRNA expression

 

VEGF-C positive rate (%)

 

Tissue type

Metastasis

Non-metastasis

P

Metastasis

Non-metastasis

P

Cancer tissues

2.27 ± 0.39

2.92 ± 0.48

0.455

68.4 (13/19)

90.9 (20/22)

> 0.05

Normal tissues

0.95 ± 0.18

1.18 ± 0.27

0.948

47.4 (9/19)

45.5 (10/22)

> 0.05

Lymph nodes

1.21 ± 0.23

1.46 ± 0.24

0.314

68.4 (13/19)

9.1 (2/22)

< 0.001*

  1. * P < 0.05 is considered statistically significant
  2. Within parenthesis: number of eligible cases