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Figure 4 | BMC Cancer

Figure 4

From: Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: Increased expression of a CD44 variant isoform after chemotherapy

Figure 4

Two hypothetical models for the induction of CD44v8-10 after chemotherapy. Cancer cells expressing CD44v8-10 are present in the original tumor and clonally expand in response to anti-cancer drugs (a). Cancer cells with CD44v8-10 are absent from the original tumor, but oxidative stress caused by chemotherapy induces the ectopic expression of CD44v8-10 (b)

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