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Table 1 The consecutive changes of some pro-angiogenic factors in the first and re-initiated IFN-α treatment course

From: Up-regulation of platelet-derived growth factor-A is responsible for the failure of re-initiated interferon alpha treatment in hepatocellular carcinoma

Unigene Gene name Description Gene symbol Control group A IFN-α treatment group B Re- initiated control group E Re- initiated IFN-α group F
Hs.283749 NM_001145 Angiogenin, RNase A family, 5 ribonuclease ANG 0.404 0.275 0.418 0.326
Hs.2233 NM_000759 Colony stimulating factor 3 (granulocyte) CSF3 0.179 0.117 0.400 0.032
Hs.419815 NM_001963 Epidermal growth factor (beta- urogastrone) EGF 0.270 0.204 0.057 0.045
Hs.284244 NM_001006 Fibroblast growth factor 2 (basic) FGF2 0.236 0.163 0.014 0.011
Hs.396530 NM_000601 Hepatocyte growth factor HGF 0.414 0.140 0.074 0.026
Hs.308053 NM_000618 Insulin-like growth factor 1 (somatomedin C) IGF1 0.242 0.062 0.032 0.006
Hs.624 NM_000583 Interleukin 8 IL-8 0.235 0.130 0.020 0.017
Hs.367877 NM_004530 Matrix metalloproteinase 2 MMP2 0.171 0.071 0.014 0.010
Hs.151738 NM_004994 Matrix metalloproteinase 9 MMP9 0.179 0.069 0.012 0.010
Hs.376032 NM_002607 Platelet-derived growth factor alpha polypeptide PDGFA 0.212 0.054 0.131 0.200
Hs.252820 NM_002632 Placental growth factor PGF 0.050 0.021 0.040 0.008
Hs.196384 NM_000963 Prostaglandin-endoperoxide synthase 2 PTGS2 0.137 0.063 0.069 0.041
Hs.170009 NM_003236 Transforming growth factor, alpha TGFA 0.169 0.082 0.080 0.028
Hs.241570 NM_000594 Tumor necrosis factor (TNF superfamily, member 2) TNG 0.076 0.044 0.097 0.026
Hs.73793 NM_003376 Vascular endothelial growth factor VEGF 0.203 0.100 0.199 0.092