The protein expression patterns of CHD1L in primary ovarian lesions and in metastatic leisions. (A) Negative expression of CHD1L protein was observed in a primary ovarian lesions (case 75), in which less than 10% tumor cells revealed positive immunostaining of CHD1L in nuclei (upper panel, ×40). (B) A primary ovarian lesion case (case 45) demonstrated positive expression of CHD1L protein, in which more than 80% of tumor cells showed high immunoreactivity of CHD1L protein in nuclei (upper panel, ×40). (C) Positive expression of CHD1L protein was demonstrated in a metastatic ovarian lesion case (case 20, upper panel, ×40). The lower panels indicated the higher magnification (×200) from the area of the box in A, B and C respectively.