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Table 1 Clinical characteristics of 874 lung cancer patients treated with paclitaxel-based chemotherapy

From: Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study

Description of patients who received taxane-based chemotherapy

 

Total (N = 874)

Age at Diagnosis

 

 Mean (SD)

61.8 (10.4)

 Median (range)

63.0 (34.0-86.0)

Gender

 

 Female

392 (44.9%)

 Male

482 (55.1%)

Cigarette smoking status

 

 Never smokers

158 (18.1%)

 Former smokers

428 (49%)

 Current smokers

273 (31.2%)

 Some smokers

15 (1.7%)

Stage

 

 SCLC

 

 Limited

37 (4.2%)

 Extensive

39 (4.5%)

 NSCLC

 

 Stage I and II

153 (17.5%)

 Stage III

328 (37.5%)

 Stage IV

317 (36.3%)

Histologic cell type

 

 Adenocarcinoma/bronchioloalveolar carcinoma

465 (53.2%)

 Squamous cell carcinoma

162 (18.5%)

 Small cell carcinoma

76 (8.5%)

 Large cell carcinoma

28 (3.2%)

 Mixed and unspecified NSCLC

131 (15.0%)

 Others

12 (1.4%)

Tumor differentiation grade

 

 Well differentiated

76 (8.7%)

 Moderately differentiated

332 (38.0%)

 Poor/undifferentiated

395 (45.2%)

 Nongradable or unknown

71 (8.1%)

Surgery, chemotherapy, radiation

 

 Chemotherapy

238 (27.2%)

 Surgery & chemotherapy

157 (18%)

 Radiation & chemotherapy

311 (35.6%)

 Surgery & radiation & chemotherapy

168 (19.2%)

  1. Stage for NSCLC is described on the basis of the tumor-node-metastasis classification. The small cell lung cancer stage is described as suggested by the American Cancer Society as either “Extensive” or “Limited.” Abbreviations: SCLC, small cell lung cancer, NSCLC, non-small cell lung cancer.