Table 2 Multivariable analysis revealed that the pre-operative CRP-level is an independent prognostic marker for cancer- specific survival
From: Validation of CRP as prognostic marker for renal cell carcinoma in a large series of patients
Variable | P value | HR (95%CI) |
|---|---|---|
Age [years] 1 | <0.001 | 1.03 (1.01-1.04) |
Sex | 0.74 | |
female | 1 | |
male | 0.96 (0.72-1.26) | |
T stage | 0.07 | |
pT1a | 1 | |
pT1b | 0.74 | 1.08 (0.69-1.69) |
pT2 | 0.34 | 1.30 (0.76-2.22) |
pT3a | 0.006 | 1.90 (1.20-2.99) |
pT3b | 0.20 | 1.35 (0.86-2.13) |
pT3c | 0.35 | 2.00 (0.46-8.59) |
pT4 | 0.89 | 0.94 (0.42-2.20) |
LN metastases 2 | <0.001 | |
N- | 1 | |
N+ | 3.59 (2.46-5.25) | |
Pulmonary or visceral metastases 2 | <0.001 | |
M- | 1 | |
M+ | 3.23 (2.31-4.50) | |
Differentiation | 0.02 | |
G1 | 1 | |
G2 | 0.01 | 1.97 (1.16-3.34) |
G3 | 0.003 | 2.47 (1.36-4.51) |
G4 | 0.01 | 4.13 (1.38-12.34) |
Histological subtype | 0.17 | |
non ccRCC | 1 | |
ccRCC | 1.43 (0.85-2.41) | |
CRP-value 2 | <0.001 | |
<4 mg/l | 1 | |
4-10 mg/l | 0.03 | 1.66 (1.06-2.59) |
>10 mg/l | <0.001 | 2.58 (1.83-3.64) |