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Table 1 Clinical data of patients 1369, 2295 and 3133 from whom the cell lines were derived

From: Derivation and characterization of matched cell lines from primary and recurrent serous ovarian cancer

 

Patients

Clinical parameters

1369

2295

3133

112 1

1946 2

Age at diagnosis

58

59

52

42

75

Tumor type

adenocarcinoma

adenocarcinoma

adenocarcinoma

adenocarcinoma

adenocarcinoma

Histopathology sub-type

serous papillary

serous

serous papillary

endometrioid

serous papillary

Tumor grade

G3

G3

G3

G3

G3

Disease stage

IIIC

IIIC

IIIC

IIIC

IIIC

Ascites at surgery

yes

yes

yes

yes

yes

Surgical debulking

sub-optimal

sub-optimal

sub-optimal

sub-optimal

sub-optimal

Progression

yes

yes

yes

yes

yes

Death

yes

yes

yes

yes

yes

Cause of death

disease progression

disease progression

disease progression

disease progression

disease progression

Follow up (months)

28

11

22

1

0.3

Treatment

paclitaxel/carboplatin

cisplatin/topotecan

paclitaxel/carboplatin

  
 

doxorubicin

paclitaxel/carboplatin

doxorubicin

  
 

topotecan

doxorubicin

carboplatin/gemcitabine

  

Previous history of cancer

breast cancer

    

Previous chemotherapy

doxorubicine cyclophosphamide docetaxel

    
  1. 1[13].
  2. 2[19] Details pertaining to patients 112 and 1946 are also included, from previous published work.