Protein markers of cancer-associated fibroblasts and tumor-initiating cells reveal subpopulations in freshly isolated ovarian cancer ascites

Table 2 Statistical analysis of relative protein expression as based on densitometry

A. Comparison of M- and S-type samples, using Mann–WhitneyUtest/Independentt-test
Variable	Sample size (n) Sample type		Median (IQR)¹Sample type		Mann– Whitney U	p-value Exact Sign. (2-tailed)
	M	S	M	S
β-F1-ATPsynth.	18	9	0.74 (0.76)	0.66 (0.86)	72.0	0.659
100 K	18	9	1.9 (9.6)	29 (33.15)	33.0	0.012 *
ABCG2	18	9	0.17 (0.63)	0.06 (0.26)	52.5	0.148
CD44	18	9	0.13 (0.20)	0.00 (0.00)	8.50	<0.001 **
E-cadherin	18	9	0.71 (5.2)	8.6 (7.2)	31.0	0.009 **
Nanog	18	9	0.52 (0.72)	0.92 (2.21)	70.5	0.605
Oct-4A	18	9	1.1 (3.0)	0.02 (0.48)	26.0	0.003 **
SUMO-Oct-4A	18	9	0.96 (1.0)	0.45 (0.80)	34.0	0.014 *
TFAM	18	9	0.77 (1.0)	0.51 (2.0)	79.0	0.929
Vimentin	18	9	0.69 (0.8)	0.05 (0.10)	11.0	<0.001 **
Variable	Sample size (n) Sample type		Mean (± Std.deviation) Sample type		t-value	p-value Signif. (2-tailed)
Variable	M	S	M	S	t-value	p-value Signif. (2-tailed)
α-SMA	17	8	1.8(±1.1)	0.86(±0.30)	3.042	0.006² **
EpCAM	18	9	0.90(±0.47)	0.87(±0.44)	0.130	0.897³
Variable	Sample size (n) Clinical stage		Mean (± Std.deviation) Clinical stage		t-value	p-value Signif. (2-tailed)
Variable	IIIC	IV	IIIC	IV	t-value	p-value Signif. (2-tailed)
α-SMA	17	8	1.1(±0.67)	2.3(±0.46)	−2.401	0.006² **

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