Figure 2

Microarray analysis performed with TIGR MeV program: principal component analysis. Microarray analysis of cultured human GBM cells generating tumor xenografts with nodular-like growth pattern, NL-type (PT1-3) or highly diffuse and invasive growth pattern, HD-type (PT4-6). Probe sets associated to dysregulation of gene expression levels among the six samples were identified using SAM (see Materials and Methods). Principal component analysis (PCA) is shown to provide the 2D projections onto the plane spanned by the two principal components for the data sets for each patient.