Over-expressions of AMPK subunits in ovarian carcinomas with significant clinical implications

BMC Cancer

Table 2 Summary of association between high expression of AMPK subunits and clinical data

AMPK subunit	Chromosomal location	Cell type	Grade	Stage	Recurrence
Alpha 1	5p13	Mucinous^*	NC	NC	NC
Alpha 2	1p32	Endometrioid	NC	NC	Lower rate
Beta 1	12q24	Mucinous	NC	Early	NC
Beta 2	1q21	Mucinous	NC	NC	NC
Gamma 1	12q13	Serous	NC	NC	NC
Gamma 2	7q36	Serous	Low	Late	NC

^*Although AMPK-α1 is not generally significantly over-expressed in ovarian cancer, high expression of the AMPK-α1 still has an association with mucinous carcinoma (Additional file 2: Table S1). NC = No Correlation.

ISSN: 1471-2407