Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer

Table 9 Univariate and multivariate analyses on the association between clinical parameters and the discordance rates of KRAS mutation status ^a

Characteristic	Univariate analysis			Multivariate analysis
	Concordant cases, N (%)	Discordant cases, N (%)	P	OR (95 % CI)	P
Metastatic site			0.019
Liver	42 (89.4)	5 (10.6)		1 (Referent)
Lung	25 (67.6)	12 (32.4)		4.03 (1.27-12.80)	0.018
Others	51 (86.4)	8 (13.6)		1.32 (0.40-4.33)	0.649
Tumor site			0.047
Colon	93 (86.1)	15 (13.9)		-
Rectum	25 (71.4)	10 (28.6)		-	-
Type of primary tumor specimens			0.073
Resected	112 (84.2)	21 (15.8)		-
Biopsied	6 (60.0)	4 (40.0)		-	-

^a In multivariate analysis, only variables which had P-values < 0.10 in univariate analysis were included.
Abbreviations: OR, odds ratio; CI, confidence interval.

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