Skip to main content

Advertisement

Table 9 Univariate and multivariate analyses on the association between clinical parameters and the discordance rates of KRAS mutation status a

From: Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer

Characteristic Univariate analysis   Multivariate analysis
  Concordant cases, N (%) Discordant cases, N (%) P OR (95 % CI) P
Metastatic site    0.019   
 Liver 42 (89.4) 5 (10.6)   1 (Referent)  
 Lung 25 (67.6) 12 (32.4)   4.03 (1.27-12.80) 0.018
 Others 51 (86.4) 8 (13.6)   1.32 (0.40-4.33) 0.649
Tumor site    0.047   
 Colon 93 (86.1) 15 (13.9)   -  
 Rectum 25 (71.4) 10 (28.6)   - -
Type of primary tumor specimens    0.073   
 Resected 112 (84.2) 21 (15.8)   -  
 Biopsied 6 (60.0) 4 (40.0)   - -
  1. a In multivariate analysis, only variables which had P-values < 0.10 in univariate analysis were included.
  2. Abbreviations: OR, odds ratio; CI, confidence interval.