| Â | Concordant cases, N (%) | Discordant cases, N (%) | Total N |
P-value |
|---|
Liver | 42 (89.4) | 5 (10.6) | 47 | - |
Lung | 25 (67.6) | 12 (32.4) | 37 | 0.014 |
Peritoneum | 26 (86.7) | 4 (13.3) | 30 | 0.730 |
Distant lymph nodes | 15 (88.2) | 2 (11.8) | 17 | 1.000 |
Ovary | 9 (81.8) | 2 (18.2) | 11 | 0.607 |
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a The discordant rates of KRAS mutation status between primary tumors and respective metastatic sites (lung, peritoneum, distant lymph nodes and ovary) were compared with the discordant rate of KRAS status between primary tumor and hepatic metastatic sites (10.6%) using the Pearson’s chi square or Fisher’s exact tests.
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b The KRAS discordant rate of lung metastasis (32.4%; 12/37) was also significantly higher when compared with the discordant rate of combining all other metastatic organs [12.3%; 13/106 (P = 0.005)].
