Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer

Table 7 Multivariate logistic regression analysis on the correlation between clinical parameters including KRAS status and liver- or lung-only metastases ^a

Clinical parameter	Liver-only metastasis		Lung-only metastasis
	OR (95% CI)	P	OR (95% CI)	P
KRAS status (MT vs. WT)	0.24 (0.10-0.55)	0.001	4.20 (1.43-12.33)	0.009
Tumor site (rectum vs. colon)	-	-	3.32 (1.15-9.59)	0.026
Clinical situations for the development of systemic metastasis (recurred vs. stage IV)	0.22 (0.085-0.57)	0.002	6.24 (2.32-16.77)	< 0.001

^a In this analysis, only variables which had P-values < 0.10 in univariate analysis were included in patients with single organ-only metastasis (N = 113).
Abbreviations: OR, odds ratio; CI, confidence interval; MT, mutant-type; WT, wild-type.

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