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Table 4 Analyses of KRAS discordance patterns in KRAS discordant cases (N = 25)

From: Different metastatic pattern according to the KRAS mutational status and site-specific discordance of KRAS status in patients with colorectal cancer

Characteristic WT (P) → MT (M) MT (P) → WT (M) Total N P-value
  N (%) N (%)   
Clinical situations for the development of systemic metastasis     0.411
 Stage IV at the time of initial diagnosis 7 (43.8) 9 (56.3) 16  
 Recurred after curative resection 6 (66.7) 3 (33.3) 9  
Analyzed metastatic sites     0.377
 Liver 1 (20.0) 4 (80.0) 5  
 Lunga 6 (50.0) 6 (50.0) 12  
 Distant lymph nodes 1 (50.0) 1 (50.0) 2  
 Peritoneum 3 (75.0) 1 (25.0) 4  
 Ovary 2 (100.0) 0 (0.0) 2  
  1. Abbreviations: WT, wild-type; P, primary tumors; MT, mutant-type; M, paired metastatic sites.
  2. a There was no statistically significant difference in the KRAS discordance pattern between the lung and other paired metastatic organs (P = 1.000).