An association between hOGG1Ser326Cys polymorphism and the risk of bladder cancer in non-smokers: a meta-analysis

Table 5 The ORs of hOGG1 Ser326Cys polymorphisms according smoker status

Allele and genotype	Populations	OR	I ²(%)	P _{heterogeneity}	Analysis model	P
326Cys allele versus 326Ser allele (additive model) ^a	Smoker subjects	1.29 (0.97-1.71)	0%	0.64	Fixed	0.08
326Cys allele versus 326Ser allele (additive model) ^a	Non-smoker subjects	1.59 (1.08, 2.32)	0%	0.65	Fixed	0.02
Cys/Cys versus Ser/Ser (homozygote contrast) ^a	Smoker subjects	1.46 (0.84, 2.56)	0%	0.66	Fixed	0.18
Cys/Cys versus Ser/Ser (homozygote contrast) ^a	Non-smoker subjects	2.93 (1.43, 5.99)	37%	0.21	Fixed	0.003
Cys/Cys versus Cys/Ser + Ser/Ser (recessive genetic model) ^a	Smoker subjects	1.54 (1.00, 2.37)	0%	0.44	Fixed	0.05
	Non-smoker subjects	2.41 (1.47, 3.95)	0%	0.42	Fixed	0.0005
Cys/Cys + Cys/Ser versus Ser/Ser (dominant genetic model) ^a	Smoker subjects	0.72 (0.26, 2.02)	87%	0.004	Random	0.53
	Non-smoker subjects	1.58 (0.72, 3.50)	75%	0.02	Random	0.26

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