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Table 4 The main ORs of  hOGG1  Ser326Cys polymorphisms in the meta-analysis

From: An association between hOGG1Ser326Cys polymorphism and the risk of bladder cancer in non-smokers: a meta-analysis

Allele and genotype Populations OR  I   2 (%)  P  heterogeneity Analysis model  P 
326Cys allele versus 326Ser allele (additive model) a All populations 1.06 (0.90, 1.26) 64% 0.01 Random 0.49
Caucasian populations 0.95 (0.85, 1.06) 30% 0.23 Fixed 0.38
  Asian populations 1.14 (0.82, 1.57) 75% 0.02 Random 0.44
  Hospital-based 1.00 (0.90, 1.11) 51% 0.07 Random 0.99
  Studies in HWE 1.01 (0.91, 1.44) 65% 0.02 Random 0.83
Cys/Cys versus Ser/Ser (homozygote contrast) a All populations 1.11 (0.74, 1.66) 65% 0.009 Random 0.63
Caucasian populations 0.87 (0.66, 1.16) 0% 0.41 Fixed 0.35
  Asian populations 1.34 (0.64, 2.83) 78% 0.01 Random 0.44
  Hospital-based 0.97 (0.65, 1.45) 54% 0.06 Random 0.89
  Studies in HWE 1.12 (0.71, 1.79) 71% 0.004 Random 0.62
Cys/Cys versus Cys/Ser + Ser/Ser (recessive genetic model)a All populations 1.05 (0.65, 1.70) 79% <0.0001 Random 0.85
  Caucasian populations 0.85 (0.65, 1.21) 25% 0.26 Fixed 0.25
  Asian populations 1.26 (0.50, 3.17) 89% <0.0001 Random 0.62
  Hospital-based 0.89 (0.57, 1.38) 66% 0.01 Random 0.59
  Studies in HWE 1.14 (0.67, 1.94) 81% <0.0001 Random 0.64
Cys/Cys + Cys/Ser versus Ser/Ser (dominant genetic model) a All populations 1.07 (0.87, 1.32) 58% 0.03 Random 0.53
  Caucasian populations 1.04 (0.74, 1.47) 75% 0.007 Random 0.82
  Asian populations 1.16 (0.91, 1.47) 0% 0.85 Fixed 0.23
  Hospital-based 1.07 (0.83, 1.36) 64% 0.02 Random 0.61
  Studies in HWE 0.97 (0.86, 1.09) 0% 0.45 Fixed 0.59
  1. a: The reference groups are the second genotypes.