Table 1 Correlation between CDCA3 expression and clinical classification in OSCCs
Results of immunostaining | ||||
|---|---|---|---|---|
Clinical classification | No. patients (%) | |||
Total | CDCA3 negative | CDCA3 positive | pvalue | |
Age at surgery (years) | ||||
<60 | 23 | 9 (39) | 14 (61) | |
≧60, <70 | 22 | 11 (50) | 11 (50) | 0.852 |
≧70 | 50 | 22 (44) | 28 (56) | |
Gender | ||||
Male | 58 | 28 (48) | 30 (52) | 0.317 |
Female | 37 | 14 (38) | 23 (62) | |
T-primary tumor | ||||
T1 | 6 | 3 (50) | 3 (50) | 0.020* |
T2 | 56 | 30 (54) | 26 (46) | |
T3 | 15 | 5 (33) | 10 (67) | |
T4 | 18 | 4 (22) | 14 (78) | |
T1 + T2 | 62 | 33 (53) | 29 (47) | 0.015* |
T3 + T4 | 33 | 9 (27) | 24 (73) | |
N-regional lymph node | ||||
N (−) | 56 | 25 (45) | 31 (55) | 0.919 |
N (+) | 39 | 17 (44) | 22 (56) | |
Stage | ||||
I | 6 | 3 (50) | 3 (50) | 0.235 |
II | 36 | 18 (50) | 18 (50) | |
III | 17 | 8 (47) | 9 (53) | |
IV | 36 | 13 (36) | 23 (64) | |
Histopathologic type | ||||
Well | 60 | 26 (43) | 34 (57) | 0.803 |
Moderately | 31 | 14 (45) | 17 (55) | |
Poorly | 4 | 2 (50) | 2 (50) | |
Tumor site | ||||
Gingiva | 28 | 9 (32) | 19 (68) | 0.456 |
Tongue | 51 | 25 (49) | 26 (51) | |
Buccal mucosa | 9 | 4 (44) | 5 (56) | |
Oral floor | 7 | 4 (57) | 3 (43) | |