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Table 1 Differentially expressed genes in U-266-1970-Stat1C cells versus U-266-1970-pcIneo cells, untreated or IFN-γ-treated

From: Stat1 activation attenuates IL-6 induced Stat3 activity but does not alter apoptosis sensitivity in multiple myeloma

MLPA probe

Corresponding gene

Category

Fold expression in Stat1C vs pcIneo

Fold expression in Stat1C/IFN-γ vs pcIneo/IFN-γ

PMAIP1-RO1

Noxa

Bcl-2 family

4.4

5.6

  

BH3-only

  
  

Pro-apoptotic

  

HRK-R01

Harakiri

Bcl-2 family

9.1

28.5

  

BH3-only

  
  

Pro-apoptotic

  

MCL1-R02

Mcl-1 short

Bcl-2 family

11.2

13.4

  

Bax-like

  
  

Pro-apoptotic

  

BCLG-R01

Bcl-GS

Bcl-2 family

n.s.

2.8

  

Bax-like

  
  

Pro-apoptotic

  
  1. (P < 0.005, > 2-fold difference).